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Several studies have suggested that the epithelial barrier is compromised in rodents exposed to various forms of PM ( 10 led to increased epithelial permeability in rat lungs, as indicated by enhanced total protein levels in bronchoalveolar lavage (BAL) fluid, which was associated with cell toxicity and inflammation ( 2.5 , these particles reduced the expression of E-cadherin in the lung tissue, which was linked to an increase in inflammatory cytokines in the BAL fluid ( 4 Inflammatory effects of PM on airways The vast majority of the literature suggests increases in inflammatory changes in the airways and lungs following PM exposure ( Figure 1 )

Flow cytometry Bacteria labelled with either 488 or Cy5 were washed and resuspended in 100 l 1 PBS

14.3 Inflammation and Seminal Tract Infections Male accessory gland infections (MAGI) indicate infection and/or inflammation of accessory glands such as the prostate, seminal vesicles, and Cowpers glands