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Description

-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury

10.1105/tpc.016980 94 LiL.ZhuF.LiuH.ChuA.LoC

Trends Endocrinol Metab 26, 212220

For instance, a study conducted in 2021 demonstrated that vitamin C can induce autophagy, degrade ferritin, release free iron, and initiate the Fenton reaction to generate ROS (83)