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In this context, CHAC2 expression promotes cancer growth, inhibits apoptosis and accelerates cell cycle progression through MAPK hyperactivation (Peng et al., 2023)

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The cellular experiments found that crocin skewed the polarization of glial BV-2 cells from the inflammatory M1 phenotype to the M2 phenotype by inhibiting the NF-kB and NLRP3 signaling pathway (96)

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