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Evaluations in unilateral tinnitus patients have demonstrated a negative correlation between cochlear nerve fiber thickness and both hearing loss and tinnitus severity, with similar relationships observed in retinal nerve fiber layer thickness, suggesting a possible underlying neurodegenerative component in the disease etiology (Avcu et al., 2021)

Alpha-ketoglutarate ameliorates induced premature ovarian insufficiency in rats by inhibiting apoptosis and upregulating glycolysis

In situ reduction by NaBH 4 (3 mM) converted 32 to stable conjugate 33

Mechanical disruption, however, does not promote proteolysis and the extracts it produces contain little peptide, or free amino acid, meaning that it is well-suited to producing extracts high in vitamins and antioxidants, but not for flavorings, which require a high content of amino acid [58]