Toxicity from high doses of B12 is fairly unlikely as it is a water-soluble vitamin, so any excess will be flushed out
A deficiency can also cause issues such as diarrhea, nausea, vomiting, lack of appetite, weight loss, pale skin, numbness and tingling in your hands and feet, confusion, irritability, depression, and behavior changes
Vitamin B12 functions in the body through two bioactive coenzymes: Methylcobalamin Functions in the cell plasma as a coenzyme in the methylation cycle Adenosylcobalamin Functions in the mitochondria as a coenzyme in the citric acid cycle Through these two functional mechanisms, multiple effects take place in diverse biological systems as explored in our article: Vitamin B12 Benefits The focus of this article is on methylcobalamin and its working within the methylation cycle
(2023) study provides important evidence about the impact of disposable cystoscope use on clinical practice and demonstrates one of the substantial clinical improvement claims for single-use cystoscopes