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Mohamed SY, Kaf RM, Ahmed MM, Elwan A, Ashour HR, Ibrahim A

Hass and Barnstable found that knocking out Mitochondrial Uncoupling Protein 2 (UCP2) in astrocytes, a glial cell that interacts with RGCs, restored respiratory capacity and increased mitophagy (as measured by LC3B and Tom20 colocalization) inside astrocytes and promoted RGC survival in microbead occlusion model of ocular hypertension (Hass and Barnstable, 2019)

These ROS function as effectors in the downstream stress response, serving as signaling molecules that contribute to the plant's adaptive mechanisms and enhance stress tolerance (Bose et al

Animal research provides valuable mechanistic understanding but doesn't guarantee identical effects or safety in humans