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This is a crucial observation and is likely to become a key element of medicinal chemistry strategies in the design of potent, selective, and safe kinase inhibitors

Additionally, deoxyschisandrin suppressed H2O2-induced NF-kappaB activation by inhibiting IkappaBalpha degradation and NF-kappaB translocation to the nucleus, suggesting its potential as a protective agent against oxidative stress-induced intestinal cell apoptosis [481]