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While these dont usually reduce contraceptive effectiveness, spacing doses apart is a good practice

Statistical analysis All the statistical data are presented as mean SEM

In a randomized single-blind, placebo-controlled clinical trial, black cumin supplement (NS-1, NS-2 = 1, 2 g/day, respectively, for 3 months) given to partly controlled asthma patients with maintenance inhaled therapy increased peak expiratory flow (PEF) by 575% in higher dose NS-2 group

The results showed that serum AST and ALT levels were up-regulated in the NOD mice ( p = 0.0021 and 0.0048), but were significantly recovered after the GSH administration ( p = 0.0081 and 0.0263)