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Eltrombopag was administered at an initial dose of 50 mg once daily for 2 weeks and increased over 2-week periods up to a maximum dose of 150 mg once daily

10.1016/j.jhep.2013.12.019 6 BaraonaE.LieberC

Phytomedicine 129, 155675

Thus, the killing of MB cells is the result among positive and negative signals transduced by activating or inhibiting receptors upon binding with the corresponding ligands on MB cells ( Figure 2 )