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24.2% weight loss at 48 weeks Massive metabolic improvements More research needed on long-term safety Other GLP-1/Glucagon Drugs Survodutide, Pemvidutide, and Cotadutide are in earlier or mid-stage development, with Survodutide showing the strongest results so far

Fura-2 emission was obtained by exciting alternatively at 340 and 380 nm with a rotating filter wheel (Sutter Instruments) and by monitoring emissions (F340 and F380) at 510 nm

Superoxide dismutase (SOD) activity was quantified using a commercial kit, based on the inhibition of WST-1 formazan dye generation

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