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Patients should seek urgent same-day assessment if they develop any new neurological symptoms, as subacute combined degeneration of the spinal cord a serious but preventable complication of prolonged B12 deficiency requires immediate treatment

The research cited may not reflect the full body of available evidence, and findings from preclinical studies may not translate to human outcomes

Long-term human safety data beyond 12 weeks doesnt exist yet, so protocols requiring extended dosing should implement appropriate monitoring