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Introduction of a second Cys at a later stage may then enable disulfide formation subject to further constraints

Metabolism Rate: Faster metabolism may lead to quicker results but may also require more frequent dosing

ZHOU S, SUN L, QIAN S, et al

To transcriptionally downregulate HER2, we devised a strategy to selectively disrupt the ELF3-MED23 proteinprotein interaction (PPI), which is specific to HER2 regulation