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Sleep apnea occurs predominantly in middle-aged men and postmenopausal women and is associated with obesity and cardiovascular complications, including hypertension, while narcolepsy and idiopathic hypersomnia are chronic brain disorders with an onset at a young age (5)

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With the rise of precision nanomedicine, HA-coated nanoparticles and hydrogels will continue to evolve as vehicles for targeted drug delivery, especially in oncology, where CD44 receptor-mediated targeting is showing consistent promise