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Liang TT, Zhang Q, Sun WX, Xin Y, Zhang ZG, Tan Y, et al

10.1179/1476830512y.0000000004 [DOI] [PMC free article] [PubMed] [Google Scholar] Ni R., Marutle A., Nordberg A

This was done by replacing the 3,4,5-trimethoxyphenyl moiety at R 1 with several heteroarylmethylamino and hydroxylamine groups, as it was proven in the same study that the 3,4,5-trimethoxyphenyl at R 1 is not crucial for PDE5 inhibitory activity