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5, B and C ) that was limited to cells cultured in medium with cysteine levels of 0.1 and 0.3 mM, conditions under which CDO transfection was shown to significantly decrease cysteine and glutathione levels

METHOD OF ADMINISTRATION Micro-needling Mesotherapy Sytsem Topical application TREATMENT PROTOCOL Mesotherapy in 2 stages STAGE 1 TREATMENT 8 sessions, intervals of 1 week to 10 days STAGE 2 MAINTAIN 4 sessions, once a month To achieve expected outcome, L-CARNITINE mesotherapy requires a minimum of 8 sessions over 2 months plus 4 maintenance sessions

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Astrocytes were prepared from the mixed brain cell cultures using a protocol previously described by Guillemin et al