lithobates clamitus melanota Green Frog (Lithobates clamitans) Green Frog

doi:10.7759/cureus.29696 2

Loss of these metabolites, coupled with excessive activation of innate immune pathways (e.g., TLR2MyD88NFB), fosters skin inflammation, metabolic disturbances, and oxidative stress, ultimately disrupting skin immune homeostasis

Thus, it was found that activation of p38MAPK pathway played an important role in pathogenesis of CI-AKI, and Zhidahuang-Chuanxiong drug pair might alleviate renal damage in CI-AKI rats through inhibiting the activation of pathway

Then FcRn-GST (0.25 g/ml or 2.0 g/mL), biotinylated human or mouse FcRn (Immunitrack) (2.5 g/mL or 0.25 g/mL) were added and incubated for 1 h at RT