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The value of adjuvant fluoropyrimidines is further supported by the positive results of the ASCOT trial, conducted in Japan, which tested adjuvant S-1 chemotherapy versus surveillance 297

49 GLP-1RAs represent a pharmacotherapeutic category of injectable hypoglycemic agents that are sanctioned as adjunctive therapies to diet and exercise for the management of type 2 diabetes mellitus (T2DM) in adult patients and potentially hold promise in addressing other medical conditions