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Acknowledgements: This research was supported by a grant from Ministry of Science, Education and Sports, Republic of Croatia (grant number 108-1083570-3635)

Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma

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While long-term use has not shown safety concerns in available data, cycling helps prevent metabolic adaptation and may maintain the peptides effectiveness across multiple rounds