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10.1016/j.actbio.2017.06.006 12 BowlesR

Cold exposure does it

Mitochondrial iron metabolism in cancer Mitochondria serve as the central hub for iron utilization in cancer cells, directly linking iron metabolism to tumor bioenergetics, redox balance, and therapeutic resistance

However, further retrospective case series have identified liver injury and hepatotoxicity in children following paracetamol intoxication, particularly following multiple sequential overdoses , and that the mortality in these cases can be high