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Nielsen RL, Wolthers BO, Helenius M, Albertsen BK, Clemmensen L, Nielsen K, et al

Knocking down ICA69 reversed GPX4 inhibition, attenuated intracellular ferroptosis production and improved mouse survival and cardiac function [93]

81 Besides, SAM can participate in lipid synthesis through the phosphotidylethanolamine N-methyltransferase pathway, which is essential for forming very-low-density lipoproteins (VLDLs)