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[37] demonstrated that HDAC inhibitors including VPA suppressed cytokine production (Including TNF-) and induced apoptosis and histone acetylation which reduced the risk of malignancies

Anaesth 129, e38e40

Methods This was a prospective analytical study of 28 critically ill patients with a septic shock who were monitored from admission (initial) to 3 days of stay (final) in the intensive care unit (ICU)

Among these compounds, erastin, sulfasalazine (SAS), RSL3, sorafenib, and FIN56 induce ferroptosis through the inhibition of the GSH/GPX4 pathway (201, 202)