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In the context of patients with cancer these factors can be altered either by the tumor itself or the treatment, for example the hepatic lesion produced by some drugs, even changing the lipid metabolism, affecting the endogenous production of PUFAs n-3 [21], this is important because as Valenzuela et al., the liver is the organ with the greatest capacity to synthesize PUFAs in mammals [22], hence supplementation could be a way to obtain them

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Moisture or residue can compromise even the best sealant