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The reason cited is body size and a generally lower baseline GH-response threshold

In the STEP 1 extension, participants who stopped semaglutide regained about two thirds of their lost weight within a year, and cardiometabolic improvements reverted toward baseline

Especially for areas like post-pregnancy abdomens or upper arms where skin laxity is a concern, this dual-action approach is incredibly valuable. The science is straightforward: when the laser gently heats tissue internally to approximately 48-50C (while keeping the skin surface comfortable and safe), it triggers a healing response that includes immediate collagen contraction followed by regeneration

Liver function tests (AST, ALT, bilirubin) and kidney function tests (creatinine, eGFR)