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This resulted in elevated activity of Caspase-3 and Caspase-9, increased expression of the pro-apoptotic protein Bax, decreased expression of the anti-apoptotic protein Bcl-2, and ultimately promoted apoptosis in PASMCs

Senti, G., von Moos, S

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After three months, those receiving royal jelly had greater improvement in sexual and urinary function and quality of life than those receiving estrogen or lubricant, although laboratory testing showed estrogen therapy was the most effective for reversing vaginal atrophy