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In summary, the ameliorative effects of aerobic exercise on MAFLD are primarily mediated by the activation of AMPK and its downstream related signaling pathways (Fig

2012 Feb;42(1):71-8

doi: 10.1016/j.cmet.2011.03.009 26

For example, LNP formulations can be functionalized with ligands or engineered with biomimetic surface coatings to emulate the targeting and fusion capabilities of EVs