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in selected preclinical models, co-administration with levodopa appeared to modulate levodopa response and adverse-effect readouts

doi: 10.1074/jbc.M703039200 47 AldiniGDominguesMRSpickettCMDominguesPAltomareASanchez-GomezFJet al

[114] [12] [118] [117] Hilary Goldstein of IGN felt that the game "sets a new benchmark for open-world games", [119] and Andrew Reiner of Game Informer wrote that the game "completely changes the landscape of gaming"