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Aabel, S., et al

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While long-term treatment with the HDAC inhibitor vorinostat is well tolerated (54), it remains to be determined whether treatment restricted to a critical window of development would produce self-sustaining neural changes and confer beneficial outcomes

FIGURE 1 Exogenous ROS Environmental triggers, such as exposure to cigarette smoke, UV radiation, heavy metal ions, ozone, allergens, drugs or toxins, pollutants, pesticides, or insecticides, may all contribute to the increase of ROS production in cells (Mahajan et al., 2018