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In every primate study, kidney effects emerged as the primary side effect

10.1046/j.0960-7412.2001.01232.x Plant J

Tumor progression was measured by bioluminescence imaging on a LabeoTech trans fluorescence imager after intraperitoneal injection of luciferine (3.6 mg in 120 L, Perkin-Elmer), once a week until mice reached a clinical endpoint (reduced mobility and/or abdominal distension)