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These conditions are driven by oxidative stress and mitochondrial dysfunction, which lead to the degeneration of retinal cells, including RGCs and photoreceptors [57]

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This heme protein has been suggested as the source of the O2- made by these cells

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Exposure of human melanocytes to UVB twice and subsequent incubation leads to cellular senescence and senescence-associated pigmentation through the prolonged p53 expression

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Annu Rev Genet 40: 409448

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