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It has been repeatedly reported that cocaine-induced oxidative stress increases the production of ROS, damages the ETC, suppresses the generation of ATP 54 , as well as compromises the antioxidative system 50,54 , and all of these eventually results in cardiac mitochondrial dysfunction 17,55

Cachexia Sarcopenia Muscle 13 , 16861703 (2022)

In recent years, numerous studies have shown that the high-altitude hypoxic environment causes nonnegligible damage to various organs and systems of the body

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