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Compounding allows the prescriber to fine-tune retinoid strength based on patient tolerance and to add agents like niacinamide for barrier supportcombinations not available in any single commercial product

Most people get enough from diet, but older adults, vegans, and those with certain medical conditions may require supplementation

The compound works where fat is more fat means more opportunity

The impaired adipogenesis is associated with stress of the endoplasmic reticulum (ER) and elevated expression of unfolded protein response (UPR), both can exacerbate the proinflammatory phenotype of preadipocytes and adipocytes [58]