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References Smith, R

Thus, these studies suggest that histone demethylases may be required for normal ethanol tolerance and ethanol-induced sedation (9193)

605 Some variants in the interferon-responsive gene OAS1 may lower its expression and potentially increase the likelihood of AD and severe COVID-19, through excessive release of pro-inflammatory signals in myeloid cells such as microglia and macrophages, further leading to cell death

The increase in deacetylated histone H3 leads to suppression of chromatin in promoter region and cause failure of gene functionality (Xia et al., 2020)