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Transcriptional profiling shows altered expression of wnt pathway- and lipid metabolism-related genes as well as melanogenesis-related genes in melasma

Conversely, the upregulation of TGF-1 induces ROS production in vascular smooth muscle and endothelial cells by activating NADPH oxidase

Triterpenoids and saponins Phytochemical investigations demonstrated that fruit, branches, and leaves of SB contain pentacyclic triterpenoids, mostly of oleanane- and ursane-type (Fig