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(PubMed) Weingarten M, Payson B

doi: 10.1073/pnas.081082098 5 DeLeveL

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It has been noted that the abundance of genes for the metabolism and biosynthesis of almost all amino acids is decreased in IBD patients ( Previous studies have demonstrated a strong association between foodborne bioactive peptides and the development of IBD ( Furthermore, there is a close relationship between lipid metabolism and IBD, with various fatty acids and lipid metabolites attenuating the expression of the TNF gene during the pathology of IBD, such as oleic acid, w-3 polyunsaturated fatty acids, arachidonic acid, and prostaglandins derived from phosphatidylcholine ( Previous studies have indicated that 1,5-anhydroglucitol (1,5-AG) is a carbohydrate-like metabolite whose enzymatic side reaction produces 1,5-anhydroglucitol-6-phosphate (1,5-AG6P)