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Following menopause, the lack of estrogen stimulation causes the myometrium and endometrium to undergo significant atrophy, resulting in a much smaller uterine volume

The findings reveal a novel regulatory mechanism of deubiquitinase USP33 in controlling the magnitude of PRKN-mediated mitophagy process, and offer the important insights into dynamic balance of ubiquitination and deubiquitination in the maintenance of mitochondrial self-homeostasis

Understanding that distinction matters before evaluating the evidence

This study was reviewed by the Institutional Review Board of the Boston University School of Medicine and was approved for exemption because it only included tissues collected from post-mortem subjects not classified as human subjects