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The probiotic bacterial strains presented antioxidative properties, which were protective in the gastrointestinal tract, favored the growth of beneficial microorganisms and mitigated endogenous and exogenous oxidative stress (Castex et al., 2009)

For the inhibitor cohort design (n = 110) , similarly, ten mice were assigned to the control group, treated with normal saline (i.t.) on Day 1 and vehicle (i.p.) on Days 1528.The remaining 100 mice were administered BLM (3.3 U/kg, i.t.) on Day 1

Two CD95 (APO-1/Fas) signaling pathways

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