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It represents the most comprehensive synthesis of randomized and controlled evidence for ALC to date, covering more than four decades of research

Internal bleeding High INR can cause bleeding in the brain, stomach, or intestines, which can be life-threatening

For instance, Peg10, Lcp2, Flt-4 (VEGFR3) , and Lyve1 exhibit higher expression in LSECs, while PECAM1 (CD31) , IL-33 , Pdgfb , and Timp3 show relatively higher expression in large vascular endothelium (Inverso et al., 2021)