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doi: 10.7150/thno.73896 53 SheltonLMHuysentruytLCSeyfriedTN

doi: 10.1016/j.isci.2024.109752

Notably, KLF2 suppresses the PI3K/AKT signaling pathway, thereby inducing ferroptosis (77)

This suggests that ferroptosis plays a crucial role in explaining the interplay between iron overload, oxidative stress, and selective dopaminergic neuron loss in PD, reinforcing its relevance in PD pathogenesis ( Figure 5 )