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BCL2 rearrangements are more common in GCB DLBCL and are associated with resistance to apoptosis, which can impact the effectiveness of radiation therapy ( BCL6 rearrangements, which are found in both ABC and GCB subtypes, can inhibit differentiation and promote survival of lymphoma cells, potentially affecting their radiosensitivity ( MYC rearrangements, often associated with a more aggressive disease course, lead to overexpression of the MYC protein, driving rapid cell proliferation and metabolic activity

In addition, large-scale epidemiological investigations and clinical studies are also needed to assess the potential association between M

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