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By increasing the activity of antioxidant enzymes such as glutathione peroxidases and thioredoxin reductases, selenium limits the excessive accumulation of ROS, thus inhibiting the overactivation of this pathway

The preclinical foundation is strong, particularly for BPC-157 and thymosin beta-4, but the gap between animal evidence and clinical application can only be bridged through rigorous controlled studies in human fracture patients

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Second, aNDBs consist of positively charged molecules (chondroitin sulfate, o-pullulan, alginate, -polylysine, chitosan, magainin-2, etc.), containing cationic groups such as quaternary ammonium, quaternary phosphonium, guanidinium, or tertiary sulfonium (Santos et al., 2016), which have a positive charge