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Relative contraindications requiring caution include active or suspected cancer (GHK-Cu promotes angiogenesis with concern about theoretically feeding tumors, though conflicting data shows documented anti-cancer gene expression effects requiring medical supervision), severe organ dysfunction (kidney or liver failure may slow peptide clearance), hemochromatosis or copper overload conditions, autoimmune disorders, and patients on immunosuppressants or blood thinners

In the 1980s, the Slavic researchers whom we have to thank for the bulk of our knowledge about short peptides were focused on the possibilities of a thymic peptide bioregulator called thymalin which they found could spur the thymus to re-grow, thus enhancing immune function

GHK-Cu is a naturally occurring copper peptide found in human plasma

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