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Funding This research was funded by the European UnionNext Generation EUunder the National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 -M4 C2, Investment 1.5-Call for Tender No

The general mechanism of its formation begins with the generation of a tyrosyl radical generated due to the removal of the hydrogen atom from the hydroxyl group on the phenoxy ring (Atwood et al., 2004

The hepatic extraction is determined both by the blood flow and by the intrinsic clearance

Research applications include studying how senescent immune cells affect vaccine efficacy, immune surveillance, and infection resistance in aging models, providing insights into interventions for age-related immune decline and immunosenescence mechanisms