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In parallel, glycolysis inhibition increased cell death in Gclc -deficient FoB to a stronger extent when compared to controls (Fig

As can be seen in this table, the median lifespan of treated populations was always greater than that of control populations, however the magnitude of the difference varied between experiments, with the median lifespan of control populations ranging from 7 to 9 days

For example, in AML, mutations in DNMT3A can result in altered de novo DNA methylation patterns, affecting gene expression and promoting the occurrence and development of leukemia

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