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Some practitioners run continuous protocols, but cycling remains the conservative approach until more long-term data exists

Dysregulation of membrane lipid peroxidation is induced by loss of the lipid detoxification enzymatic GPX4, and subsequent accumulation of lipid-based ROS, particularly lipid hydroperoxides [3, 38]

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Statistical analysis The data are presented as the mean and standard deviation (SD) and statistical analysis was performed using Prism 9 software (Graph Pad, San Diego, CA, USA)