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2J, K), and a 1.6 resolution crystal structure revealed this was due to conformational occlusion of the WD40 binding site by an inward rotation of nearby Arg13 and His31 side chains, rather than loss of Lys15 interactions (Fig

Sci Rep 14 , 5514 (2024)

Glutathione and NAC are also fairly exceptional due to their thiol group, which contains sulfur

The reduction in sperm count is reversible, and the count usually returns to normal after discontinuing sulfasalazine or by changing to a different 5-ASA compound