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This is well-documented in clinical stroke trials

Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet

Gut microbiota-derived D-serine protects against acute kidney injury

Patients of the intervention group showed a significant weight loss, but there was no significant effect detectable neither on the development of AKI during the first 7 days post-surgery, the change of urinary NGAL or serum cystatin-C nor the length of hospital stay