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It is noteworthy that the age-old Hippocratic belief that all disease originates in the gut remains relevant in modern neurobiology, with growing evidence supporting the importance of the gut-brain axis in maintaining neural well-being (130)

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Herbal prescriptions Kanglaite injection and Kushen injection have been found in clinical trials to reduce the hepatotoxicity of CDDP significantly and are expected to be used as adjunctive therapies with CDDP [55, 75, 76]

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