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It has also been reported that human GST class Omega, GSTO1-1, modulates calcium channel (ryanodine receptors, RyRs) protecting mammalian cells from apoptosis induced by calcium (Ca 2+ ) mobilization [57]

LTA 4 H, leukotriene A 4 hydrolase

Acknowledging ZBP1 expands our understanding of how aberrant mtDNA contributes to innate immune signaling in NDDs and highlights additional potential targets for therapeutic modulation of sterile inflammation [104]