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10.1038/s41380-023-02161-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 84.Cheng X, Zhang Y, Li Y, Wu Q, Wu J, Park SK, et al

Studies have shown that trypsin induces the release of calcium ions from vascular endothelial cells, causing coronary artery-dependent vasodilation and reducing the contractile sensitivity of smooth muscle [79]