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Vitamin B12 deficiency after total gastrectomy for gastric cancer, prevalence, and symptoms: a systematic review and meta-analysis

Monitoring: A history of the patients allergies/hypersensitivity should be obtained before administering cyanocobalamin injection

While a causal relationship has not been established, patients with depression or other psychiatric conditions should be monitored for changes in mood or behavior, particularly during the initial weeks of treatment or following dose adjustments

The common starting dose in community protocols is 100 mcg per shot, once daily at bedtime, on an empty stomach, for about one week